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Article

Is DFNA5 a susceptibility gene for age-related hearing impairment?

European journal of human genetics : EJHG - 1 Dec 2002

Van Laer Lut, DeStefano Anita L, Myers Richard H, Flothmann Kris, Thys Sofie, Fransen Erik, Gates George A, Van Camp Guy, Baldwin Clinton T

Abstract excerpt

A mutation in DFNA5 leads to a type of hearing loss that closely resembles the frequently observed age-related hearing impairment (ARHI). The hearing loss is sensorineural, progressive and starts at the high frequencies. As DFNA5 was considered an excellent candidate ARHI susceptibility gene, we performed linkage analysis to a quantitive measure of high frequency hearing loss. However, no significant linkage...

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Identifiers

PMID: 12461698
DOI: 10.1038/sj.ejhg.5200878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Is DFNA5 a susceptibility gene for age-related hearing impairment?PMID 12461698Read ↗

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A novel splice site mutation in DFNA5 causes late-onset progressive non-syndromic hearing loss in a Chinese family.Semantic proximity Read ↗

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