Article
Nonsyndromic hearing impairment is associated with a mutation in DFNA5.
Nature genetics - 1 Oct 1998
Van Laer L, Huizing E H, Verstreken M, van Zuijlen D, Wauters J G, Bossuyt P J, Van de Heyning P, McGuirt W T, Smith R J, Willems P J, Legan P K, Richardson G P, Van Camp G
Abstract excerpt
Nonsyndromic hearing impairment is one of the most heterogeneous hereditary conditions, with more than 40 loci mapped on the human genome, however, only a limited number of genes implicated in hearing loss have been identified. We previously reported linkage to chromosome 7p15 for autosomal domin...
Topics
- Adolescent
- Amino Acid Sequence
- Animals
- Carrier Proteins
- Child
- Child, Preschool
- Chromosome Mapping
- Female
- Genetic Linkage
- Hearing Loss, High-Frequency
- Humans
- Male
- Mice
- Molecular Sequence Data
- Mutation