Article
AB0 blood group genotyping of ancient DNA by PCR-RFLP.
International journal of legal medicine - 1 Dec 2002
Hummel Susanne, Schmidt Diane, Kahle Melanie, Herrmann Bernd
Abstract excerpt
The paper presents an PCR-RFLP-based method to determine AB0 blood groups at the genotype level. In order to ensure the applicability of the method to severely degraded DNA, new sets of primers were designed that amplify 103/104 bp and 64 bp sequences on exon 6 and exon 7 of chromosome 9, respectively. The amplification of the two PCR products and the subsequent RFLP analysis with four endonucleases was revealed...
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