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Article

COL9A3 gene polymorphism and obesity in intervertebral disc degeneration of the lumbar spine: evidence of gene-environment interaction.

Spine - 1 Dec 2002

Solovieva Svetlana, Lohiniva Jaana, Leino-Arjas Päivi, Raininko Raili, Luoma Katariina, Ala-Kokko Leena, Riihimäki Hilkka

Abstract excerpt

STUDY DESIGN: Cross-sectional. OBJECTIVES: To evaluate the interaction between the COL9A3 gene polymorphism and persistent obesity in relation to lumbar disc degeneration. SUMMARY OF BACKGROUND DATA: Obesity has been suggested to be a risk factor for disc degeneration. There is some indication for an association between collagen IX genes and lumbar disc disease characterized by sciatica. However, the interaction...

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Identifiers

PMID: 12461395
DOI: 10.1097/00007632-200212010-00008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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