Article
Quantitative analysis of multidrug-resistance mdr1 gene expression in head and neck cancer by real-time RT-PCR.
Japanese journal of cancer research : Gann - 1 Nov 2002
Tseng Ching-Ping, Cheng Ann-Joy, Chang Joseph Tung-Chieh, Tseng Chin-Hsiao, Wang Hung-Ming, Liao Chun-Ta, Chen I-How, Tseng Kelvin Chingchung
Abstract excerpt
Progression of head and neck cancer is always associated with changes of gene expression profile. In this study, we characterized the expression of multidrug-resistance mdr1 gene, which may play a role in tumorigenesis and multidrug resistance in head and neck cancer. A TaqMan one-step RT-PCR with a linear range for quantification across at least a 5 log scale of concentration of mdr1 mRNA was designed to...
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