Article
Suggestive evidence for association of two potassium channel genes with different idiopathic generalised epilepsy syndromes.
Epilepsy research - 1 Dec 2002
Chioza B, Osei-Lah A, Wilkie H, Nashef L, McCormick D, Asherson P, Makoff A J
Abstract excerpt
Several potassium channel genes have been implicated in epilepsy. We have investigated three such genes, KCNJ3, KCNJ6 and KCNQ2, by association studies using a broad sample of idiopathic generalised epilepsy (IGE) unselected by syndrome. One of the two single nucleotide polymorphisms (SNPs) examined in one of the inward rectifying potassium channel genes, KCNJ3, was associated with IGE by genotype (P=0.0097),...
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