Article
Helicobacter pylori infection in mice: Role of outer membrane proteins in colonization and inflammation.
Gastroenterology - 1 Dec 2002
Yamaoka Yoshio, Kita Masakazu, Kodama Tadashi, Imamura Shigeyoshi, Ohno Tomoyuki, Sawai Naoki, Ishimaru Atsushi, Imanishi Jiro, Graham David Y
Abstract excerpt
BACKGROUND & AIMS: Mouse models of Helicobacter pylori infection have yielded variable results with respect to colonization and inflammation. We examined whether outer membrane proteins (OMPs) or the cag pathogenicity island (PAI) was responsible for some of this variability. METHODS: C57BL/6 mice received clinical H. pylori isolates with different genotypes for the cag PAI and OMP gene switch status, as well as...
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