Mutant forms of the Azotobacter vinelandii transcriptional activator NifA resistant to inhibition by the NifL regulatory protein.

doi:10.1128/JB.184.24.6777-6785.2002

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Article

Mutant forms of the Azotobacter vinelandii transcriptional activator NifA resistant to inhibition by the NifL regulatory protein.

Journal of bacteriology - 1 Dec 2002

Reyes-Ramirez Francisca, Little Richard, Dixon Ray

Abstract excerpt

The Azotobacter vinelandii sigma(54)-dependent transcriptional activator protein NifA is regulated by the NifL protein in response to redox, carbon, and nitrogen status. Under conditions inappropriate for nitrogen fixation, NifL inhibits transcription activation by NifA through the formation of the NifL-NifA protein complex. NifL inhibits the ATPase activity of the central AAA+ domain of NifA required to drive...

Topics

Adenosine Triphosphate
Azotobacter vinelandii
Bacterial Proteins
Mutation
Nitrogen
Promoter Regions, Genetic
Transcription Factors
Transcriptional Activation

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Identifiers

PMID: 12446627
DOI: 10.1128/JB.184.24.6777-6785.2002
PMCID: PMC135469

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