Article
Disrupting hierarchical control of nitrogen fixation enables carbon-dependent regulation of ammonia excretion in soil diazotrophs.
PLoS genetics - 1 Jun 2021
Bueno Batista Marcelo, Brett Paul, Appia-Ayme Corinne, Wang Yi-Ping, Dixon Ray
Abstract excerpt
The energetic requirements for biological nitrogen fixation necessitate stringent regulation of this process in response to diverse environmental constraints. To ensure that the nitrogen fixation machinery is expressed only under appropriate physiological conditions, the dedicated NifL-NifA regulatory system, prevalent in Proteobacteria, plays a crucial role in integrating signals of the oxygen, carbon and...
Topics
- Amino Acid Substitution
- Ammonia
- Azotobacter vinelandii
- Bacterial Proteins
- Carbon
- Gene Expression Regulation, Bacterial
- Genetic Complementation Test
- Glutamate-Ammonia Ligase
- Mutation
- Nitrogen