Article
Phenotypic differences between dermal fibroblasts from different body sites determine their responses to tension and TGFbeta1.
BMC dermatology - 21 Nov 2002
Chipev Constantin C, Simon Marcia
Abstract excerpt
BACKGROUND: Wounds in the nonglabrous skin of keloid-prone individuals tend to cause large disordered accumulations of collagen which extend beyond the original margins of the wound. In addition to abnormalities in keloid fibroblasts, comparison of dermal fibroblasts derived from nonwounded glabrous or nonglabrous skin revealed differences that may account for the observed location of keloids. METHODS: Fibroblast...
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