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Type II Gonadotropin-Releasing Hormone Receptor Transcripts in Human Sperm1

1 Dec 2002

Abstract excerpt

GnRH regulates reproduction via the well-characterized mammalian pituitary GnRH receptor (type I). In addition, two homologous genes for a second form of the GnRH receptor (type II) are present in the human genome, one on chromosome 14 and the second on chromosome 1. The chromosome 14 gene is ubiquitously transcribed at high levels in the antisense orientation but lacks exon 1, required to encode a full-length...

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PMID: 12444048
DOI: 10.1095/biolreprod.101.002808

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