Article
Isolation and Characterization of the Human Gonadotropin-Releasing Hormone Gene in the Hypothalamus and Placenta
1 Mar 1990
Abstract excerpt
The GnRH gene has been cloned in several species, but the location of the promoter and the exact start of transcription have not previously been determined. To characterize the low abundance human GnRH mRNA in the hypothalamus and placenta, we have employed the polymerase chain reaction. The hypothalamus was found to have a 61-base pair first exon, and its transcriptional start site was determined. The human...
