Article
Predominance of group A KIR haplotypes in Japanese associated with diverse NK cell repertoires of KIR expression.
Immunogenetics - 1 Nov 2002
Yawata Makoto, Yawata Nobuyo, McQueen Karina L, Cheng Nathalie W, Guethlein Lisbeth A, Rajalingam Raja, Shilling Heather G, Parham Peter
Abstract excerpt
Genomic DNA from a panel of 41 healthy unrelated Japanese individuals was typed for the presence or absence of 16 KIR genes and pseudogenes. Only eight different KIR genotypes were found. Group A haplotypes outnumbered group B haplotypes in frequency by approximately 3:1, with individuals having two group A haplotypes accounting for 56% of the panel. The frequency of A haplotypes in the Japanese is higher than...
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