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Article

Diversity of killer cell immunoglobulin-like receptor genes in Pacific Islands populations.

Immunogenetics - 1 Jul 2006

Velickovic Marija, Velickovic Zlatibor, Dunckley Heather

Abstract excerpt

Killer immunoglobulin-like receptors (KIRs) regulate the activity of NK and T cells through interaction with specific HLA class I molecules on target cells. To date, 16 KIR genes and pseudogenes have been identified. Diversity in KIR gene content and KIR allelic and haplotype polymorphism has been observed between different ethnic groups. Here, we present data on the KIR gene distribution in Pacific Islands...

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PMID: 16733717
DOI: 10.1007/s00251-006-0124-3

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