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Article

Telomere maintenance in human B lymphocytes

18 Nov 2002

Abstract excerpt

Telomere shortening has been causally linked to replicative senescence in human cells. To characterize telomere-length heterogeneity in peripheral blood cells of normal individuals, we analysed the mean length of telomeric repeat sequences in subpopulations of peripheral blood leucocytes, using fluorescence in situ hybridization and flow cytometry (flow-FISH). Although the telomere length of most haematopoietic...

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PMID: 12437664
DOI: 10.1046/j.1365-2141.2002.03910.x

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