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Article

env chimeric virus technology for evaluating human immunodeficiency virus susceptibility to entry inhibitors.

Antimicrobial agents and chemotherapy - 1 Dec 2002

Fikkert Valery, Cherepanov Peter, Van Laethem Kristel, Hantson Anke, Van Remoortel Barbara, Pannecouque Christophe, De Clercq Erik, Debyser Zeger, Vandamme Anne-Mieke, Witvrouw Myriam

Abstract excerpt

We describe the development of chimeric virus technology (CVT) for human immunodeficiency virus (HIV) type 1 (HIV-1) env genes gp120, gp41, and gp160 for evaluation of the susceptibilities of HIV to entry inhibitors. This env CVT allows the recombination of env sequences derived from different strains into a proviral wild-type HIV-1 clone (clone NL4.3) from which the corresponding env gene has been deleted. An...

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Identifiers

PMID: 12435701
DOI: 10.1128/AAC.46.12.3954-3962.2002
PMCID: PMC132780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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