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Article

Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A.

Journal of virology - 1 Jun 2005

Witvrouw Myriam, Fikkert Valery, Hantson Anke, Pannecouque Christophe, O'keefe Barry R, McMahon James, Stamatatos Leonidas, de Clercq Erik, Bolmstedt Anders

Abstract excerpt

Due to the biological significance of the carbohydrate component of the human immunodeficiency virus type 1 (HIV-1) glycoproteins in viral pathogenesis, the glycosylation step constitutes an attractive target for anti-HIV therapy. Cyanovirin N (CV-N), which specifically targets the high-mannose (...

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Share to Anti-HIV Agents
Share to Antibodies, Monoclonal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

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Share to HIV Envelope Protein gp120

Share to HIV Envelope Protein gp160

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Source

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Identifiers

PMID: 15919930
DOI: 10.1128/JVI.79.12.7777-7784.2005
PMCID: PMC1143621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15919930-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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