Article
Amino acid alterations in Gp38 of host range mutants of PP01 and evidence for their infection of an ompC null mutant of Escherichia coli O157:H7.
FEMS microbiology letters - 5 Nov 2002
Morita Masatomo, Fischer Curt R, Mizoguchi Katsunori, Yoichi Masatoshi, Oda Masahito, Tanji Yasunori, Unno Hajime
Abstract excerpt
The previously isolated T-even type coliphage PP01, specifically infective to Escherichia coli O157:H7, uses the outer membrane protein OmpC as a receptor. The characterization of a spontaneous PP01-resistant strain indicated that it had lost ompC due to the deletion of a 14-kbp region upstream of and partially including ompC. Two host range mutants, able to infect an ompC null mutant, were isolated. Sequencing...
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