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Article

Virulence of an Escherichia coli O157:H7 sorbitol-positive mutant.

Applied and environmental microbiology - 1 Dec 1993

Fratamico P M, Buchanan R L, Cooke P H

Abstract excerpt

Virulence and pathogenicity of an Escherichia coli O157:H7 sorbitol-positive mutant were investigated with an infant rabbit animal model as well as a battery of in vitro assays. Total cell lysate protein profiles, outer membrane protein profiles, plasmid profiles, and levels of cytotoxic activity against Vero cells were similar in the wild-type and mutant strains. Both adhered to intestinal epithelial cells in...

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Identifiers

PMID: 8285715
DOI: 10.1128/aem.59.12.4245-4252.1993
PMCID: PMC195892

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