Article
Sulphonamide resistant commensal Neisseria with alterations in the dihydropteroate synthase can be isolated from carriers not exposed to sulphonamides.
BMC microbiology - 18 Nov 2002
Qvarnström Yvonne, Swedberg Göte
Abstract excerpt
BACKGROUND: Development of sulphonamide resistance in Neisseria meningitidis has been suggested to involve horizontal DNA-transfer from a commensal Neisseria species. In this study, we isolated commensal Neisseria from throat specimens and examined the isolates with respect to sulphonamide resistance. RESULTS: Three resistant clones were identified and the resistance phenotype could be explained by amino acid...
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