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Article

Regulation of chromatin remodeling by inositol polyphosphates.

Science (New York, N.Y.) - 3 Jan 2003

Steger David J, Haswell Elizabeth S, Miller Aimee L, Wente Susan R, O'Shea Erin K

Abstract excerpt

Chromatin remodeling is required for efficient transcription of eukaryotic genes. In a genetic selection for budding yeast mutants that were defective in induction of the phosphate-responsive PHO5 gene, we identified mutations in ARG82/IPK2, which encodes a nuclear inositol polyphosphate kinase....

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Share to Adenosine Triphosphatases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Inositol Phosphates

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Share to Phosphotransferases (Alcohol Group Acceptor)

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Source

Open in PubMed Open full text

Identifiers

PMID: 12434012
DOI: 10.1126/science.1078062
PMCID: PMC1458531

Genes

INO80

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12434012-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Regulation of chromatin remodeling by inositol polyphosphates.PMID 12434012Read ↗

Genetic analysis of chromatin remodeling using budding yeast as a model.Semantic proximity Read ↗

The product of the SNF2/SWI2 paralogue INO80 of Saccharomyces cerevisiae required for efficient expression of various yeast structural genes is part of a high-molecular-weight protein complex.Semantic proximity Read ↗

Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase.Semantic proximity Read ↗

A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation.Semantic proximity Read ↗

Involvement of actin-related proteins in ATP-dependent chromatin remodeling.Semantic proximity Read ↗

Functional characterization of the INO2 gene of Saccharomyces cerevisiae. A positive regulator of phospholipid biosynthesis.Semantic proximity Read ↗

A genetic study of signaling processes for repression of PHO5 transcription in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genetic screen for suppression of transcriptional interference reveals fission yeast 14-3-3 protein Rad24 as an antagonist of precocious Pol2 transcription termination.Semantic proximity Read ↗

A genetic screen for suppressors of hyper-repression of the fission yeast PHO regulon by Pol2 CTD mutation T4A implicates inositol 1-pyrophosphates as agonists of precocious lncRNA transcription termination.Semantic proximity Read ↗

The INO80 Chromatin Remodeler Sustains Metabolic Stability by Promoting TOR Signaling and Regulating Histone AcetylationSemantic proximity Read ↗

Opi1 mediates repression of phospholipid biosynthesis by phosphate limitation in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

PIP2 epigenetically represses rRNA genes transcription interacting with PHF8.Semantic proximity Read ↗

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