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Article

Mechanisms of regulation of phospholipase D1 by protein kinase Calpha.

The Journal of biological chemistry - 24 Jan 2003

Hu Tianhui, Exton John H

Abstract excerpt

It has been suggested that protein-protein interaction is important for protein kinase C (PKC) alpha to activate phospholipase D1 (PLD1). To determine the one or more sites on PKCalpha that are involved in binding to PLD1, fragments containing the regulatory domain, catalytic domain, and C1-C3 domain of PKCalpha were constructed and shown to be functional, but they all failed to bind and activate PLD1 in vivo and...

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Source

Identifiers

PMID: 12431982
DOI: 10.1074/jbc.M210093200

Genes

PLD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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