Article
A unique, bifunctional site-specific DNA recombinase from Mycoplasma pulmonis.
Molecular microbiology - 1 Nov 2002
Sitaraman Ramakrishnan, Denison Amy M, Dybvig Kevin
Abstract excerpt
Site-specific DNA invertible elements often control the production of bacterial surface proteins that are subject to phase variation (ON/OFF switching). Inversion of the DNA element occurs as a result of the reciprocal exchange of DNA catalysed by a specialized enzyme (recombinase) that acts at specific sites. By continually switching the orientation of the invertible element in the chromosome, and consequently...
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