Article
Activation of σ20-dependent recombination and horizontal gene transfer in Mycoplasma genitalium.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Aug 2018
Torres-Puig Sergi, Martínez-Torró Carlos, Granero-Moya Ignasi, Querol Enrique, Piñol Jaume, Pich Oscar Q
Abstract excerpt
In the human pathogen Mycoplasma genitalium, homologous recombination is under the control of σ20, an alternative sigma factor that boosts the generation of genetic and antigenic diversity in the population. Under laboratory growth conditions, σ20 activation is rare and the factors governing its intermittent activity are unknown. Two σ20-regulated genes, rrlA and rrlB, showed to be important for recombination of...
Topics
- Bacterial Proteins
- DNA, Bacterial
- Gene Expression Regulation, Bacterial
- Gene Transfer, Horizontal
- Genes, Bacterial
- Genetic Variation
- Homologous Recombination
- Mycoplasma genitalium
- Rec A Recombinases
- Sigma Factor