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Article

High-frequency rearrangements in the chromosome of Mycoplasma pulmonis correlate with phenotypic switching.

Molecular microbiology - 1 May 1992

Bhugra B, Dybvig K

Abstract excerpt

Mycoplasma pulmonis is a murine pathogen that causes chronic respiratory disease in laboratory rats and mice. Several examples of high-frequency phenotypic switching have been reported for M. pulmonis, the molecular basis of which is unknown. We report here that during growth the M. pulmonis chromosome undergoes DNA rearrangements at a high frequency. Some of the rearrangements we examined correlated with changes...

Topics

Antigenic Variation
Bacteriophages
Chromosomes, Bacterial
Cloning, Molecular
DNA, Bacterial
Mycoplasma
Phenotype
Polymorphism, Restriction Fragment Length
Recombination, Genetic
Repetitive Sequences, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1350316
DOI: 10.1111/j.1365-2958.1992.tb01553.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1350316-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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