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Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts.

Free radical biology & medicine - 15 Nov 2002

Frippiat Christophe, Dewelle Janique, Remacle José, Toussaint Olivier

Abstract excerpt

A stress-induced senescence-like phenotype is induced by exposure of human diploid fibroblasts to subcytotoxic H2O2 stress. Previous studies showed that TGF-beta1 is responsible for the induction of several biomarkers of replicative senescence within 72 h after stress: senescence-like morphology,...

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PMID: 12419465
DOI: 10.1016/s0891-5849(02)01044-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12419465-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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