Article
East Asian genotypes of Helicobacter pylori strains in Amerindians provide evidence for its ancient human carriage.
Proceedings of the National Academy of Sciences of the United States of America - 12 Nov 2002
Ghose Chandrabali, Perez-Perez Guillermo I, Dominguez-Bello Maria-Gloria, Pride David T, Bravi Claudio M, Blaser Martin J
Abstract excerpt
Phylogenies of indigenous microbes have been used as surrogates for the origins of the hosts that carry them. Conversely, polymorphisms may be used to date the spread of a microbial species when information about their host populations is available. Therefore, we examined polymorphisms in Helicobacter pylori, which persistently colonize the human stomach, to test the hypothesis that they have been ancient...
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