Article
Intravenous pamidronate treatment in osteogenesis imperfecta.
The Journal of pediatrics - 1 Oct 1997
Bembi B, Parma A, Bottega M, Ceschel S, Zanatta M, Martini C, Ciana G
Abstract excerpt
Three children with osteogenesis imperfecta, severe osteopenia, and repeated fractures were treated with cyclic infusions of aminohydroxypropylidene bisphosphonate (pamidronate) for a period ranging from 22 to 29 months. A clear clinical response was shown, with a striking reduction of new fracture episodes and a marked improvement in the quality of the patients' lives. Bone mineral density increased...
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