Article
Lewis antigen alterations in gastric cancer precursors.
Gastroenterology - 1 Feb 1992
Torrado J, Correa P, Ruiz B, Bernardi P, Zavala D, Bara J
Abstract excerpt
To explore the dynamics of the progressive loss of cell differentiation observed in the gastric precancerous process, the abnormal expression of Lea antigen in the gastric epithelium was investigated. Gastric biopsy specimens of 122 subjects with Le(a-b+) phenotype who had intestinal metaplasia of the gastric mucosa were studied. The subjects are residents of a rural area in the Colombian Andes with very high...
Topics
- Aging
- Female
- Gastric Mucosa
- Humans
- Isoantigens
- Lewis Blood Group Antigens
- Male
- Metaplasia
- Phenotype
- Precancerous Conditions
- Stomach Neoplasms
