Article
Critical increment of Lewis blood group antigen in serum by cancer found by photothermal immunoassay.
Analytical biochemistry - 1 Oct 1999
Kimura H, Kitamori T, Sawada T
Abstract excerpt
Lewis blood group antigen levels in human sera were assayed with a highly sensitive photothermal immunoassay which is based on laser-induced photothermal detection. Comparison of 32 colon cancer patients' sera and 34 healthy persons' sera showed that cancer patients' sera contained more Lewis antigens than healthy persons' sera. Le(a) antigen level in Le(a-) type persons and Le(b) level in Le(b-) type persons...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Neoplasm
- Biomarkers, Tumor
- Carcinoembryonic Antigen
- Colonic Neoplasms
- Erythrocytes
- Humans
- Immunoassay
- Lewis Blood Group Antigens
- Mice
- Phenotype
- Photochemistry
- Reference Values
- Saliva
