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Article

Baculovirus lef-12 is not required for viral replication.

Journal of virology - 1 Dec 2002

Guarino Linda A, Mistretta Toni-Ann, Dong Wen

Abstract excerpt

The baculovirus lef-12 (orf41) gene is required for transient expression of baculovirus late genes. To analyze the role of LEF-12 in the context of infected cells, two mutant viruses were constructed. Both mutants were viable in Trichoplusia ni High 5 and Spodoptera frugiperda Sf9 cells. Single-step growth curves, however, indicated that virus yields were reduced approximately fivefold in the absence of LEF-12....

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Identifiers

PMID: 12414945
DOI: 10.1128/jvi.76.23.12032-12043.2002
PMCID: PMC136896

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