Article
Recurrent lymphangiomyomatosis after transplantation: genetic analyses reveal a metastatic mechanism.
American journal of respiratory and critical care medicine - 1 Apr 2003
Karbowniczek Magdalena, Astrinidis Aristotelis, Balsara Binaifer R, Testa Joseph R, Lium James H, Colby Thomas V, McCormack Francis X, Henske Elizabeth Petri
Abstract excerpt
Lymphangiomyomatosis (LAM) is characterized by the proliferation of abnormal smooth muscle cells and cystic degeneration of the lung. LAM affects almost exclusively young women. Although lung transplantation provides effective therapy for end-stage LAM, there are reports of LAM recurrence after lung transplantation. Whether these recurrent LAM cells arise from the patient or the lung transplant donor is an area...
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