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Article

Glycoprotein gp110 of Epstein–Barr virus determines viral tropism and efficiency of infection

30 Oct 2002

Abstract excerpt

The Epstein-Barr virus (EBV) genome has been detected in lymphomas and in tumors of epithelial or mesenchymal origin such as nasopharyngeal carcinoma or leiomyosarcoma. Thus, there is little doubt that EBV can infect cells of numerous lineages in vivo, in contrast to its in vitro infectious spectrum, which appears restricted predominantly to B lymphocytes. We show here that the EBV BALF4 gene product, the...

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PMID: 12409611
DOI: 10.1073/pnas.232381299

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