Article
Rapid assessment of phenotypic resistance to protease inhibitors in human immunodeficiency virus type 1 group O.
Journal of clinical microbiology - 1 Nov 2002
Rodés Berta, Poveda Eva, Soriano Vincent
Abstract excerpt
A bacteriophage lambda-based method was used to investigate the development of resistance to protease inhibitors (PI) in one subject infected with human immunodeficiency virus (HIV) type 1 group O who underwent multiple treatment regimens over a period of 4 years. A reduction in the susceptibility to indinavir of 6-fold and a reduction in the susceptibility to saquinavir of 24-fold were recognized after long...
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