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Article

Impact of HIV-1 group O genetic diversity on genotypic resistance interpretation by algorithms designed for HIV-1 group M.

Journal of acquired immune deficiency syndromes (1999) - 1 Feb 2011

Depatureaux Agnès, Charpentier Charlotte, Leoz Marie, Unal Guillemette, Damond Florence, Kfutwah Anfunbom, Vessière Aurélia, Simon François, Plantier Jean-Christophe

Abstract excerpt

BACKGROUND: HIV-1 group O (HIV-O) is characterized by a high genetic divergence from HIV-1 group M viruses. Little is known about the therapeutic impact of this diversity. The aim of this study was to assess in a large series of samples (1) the genotypic impact of natural polymorphism of the HIV-O reverse transcriptase and protease genes; and (2) the predictive value of resistance interpretation algorithms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21233638
DOI: 10.1097/QAI.0b013e318201a904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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