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Article

Loss of sarcolemma nNOS in sarcoglycan-deficient muscle.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2002

Crosbie Rachelle H, Barresi Rita, Campbell Kevin P

Abstract excerpt

nNOS, anchored to the sarcolemma through its interactions with the dystrophin-glycoprotein complex, is dramatically reduced in dystrophin-deficient mdx mice and Duchenne muscular dystrophy patients. Recent evidence suggests that loss of nNOS in dystrophin-deficient muscle may contribute significantly to the progression of muscle pathology through a variety of mechanisms. To investigate whether nNOS plays a role...

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Source

Identifiers

PMID: 12409321
DOI: 10.1096/fj.02-0519com

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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