Article
Resistance to antiretroviral agents in individuals with HIV-1 non-B subtypes.
HIV clinical trials - 1 Jan 2000
Holguín Africa, Soriano Vincent
Abstract excerpt
Naturally occurring polymorphisms at positions involved in resistance to antiretroviral agents are frequently seen in HIV-1 non-B subtypes. Although they do not seem to affect significantly the susceptibility to antiretroviral drugs in vitro, they may facilitate the selection of different pathways and/or a more rapid emergence of drug resistance and treatment failure under not fully suppressive treatment regimens.
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