Article
Efficacy of antiretroviral therapy in individuals infected with HIV-1 non-B subtypes.
AIDS reviews - 1 Jan 2000
Holguín Africa, Ramirez de Arellano Eva, Rivas Pablo, Soriano Vincent
Abstract excerpt
The impact of HIV-1 subtype on clinical outcome following exposure to antiretroviral therapy is currently not well known. Natural polymorphisms are often present in HIV-1 non-B subtypes at positions known to be associated with drug resistance in clade B viruses. These changes might influence the emergence of drug-resistant viruses, modifying drug susceptibility and/or the virus replicative capacity. Moreover,...
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