Article
Genetic and molecular characterization of a novel iab-8 regulatory domain in the Abdominal-B gene of Drosophila melanogaster.
Development (Cambridge, England) - 1 Nov 2002
Estrada Beatriz, Casares Fernando, Busturia Ana, Sánchez-Herrero Ernesto
Abstract excerpt
Homeotic (or Hox) genes are key determinants in specifying the anteroposterior axis of most animals. The temporal and spatial expression of these genes requires the presence of large and complex cis-regulatory regions. The Abdominal-B Hox gene of the bithorax complex of Drosophila is regulated by several infraabdominal domains, which determine Abdominal-B expression in abdominal segments A5 to A9 (parasegments 10...
Topics
- Abdomen
- Animals
- DNA Transposable Elements
- Drosophila Proteins
- Drosophila melanogaster
- Embryo, Nonmammalian
- Gene Expression Regulation, Developmental
- Homeodomain Proteins
- Mutation
- Protein Structure, Tertiary
- Regulatory Sequences, Nucleic Acid
- Transcription, Genetic