Cell Cycle Synchronization of Porcine Fetal Fibroblasts by Serum Deprivation Initiates a Nonconventional Form of Apoptosis

Abstract excerpt

The success of somatic nuclear transfer depends upon the cell cycle stage of the donor nucleus and the recipient cytoplast. Recently, we established efficient cell cycle synchronization protocols for porcine fetal fibroblasts and found that serum withdrawal leads to cell death. Here, we examined whether the specific cell death induced by serum deprivation follows the conventional apoptotic pathway in porcine...

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