Article
Mixed chimerism of bone marrow CD34+ progenitor cells (genotyping, bcr/abl analysis) after allogeneic transplantation for chronic myelogenous leukemia.
Transplantation - 15 Oct 2002
Thiele Juergen, Wickenhauser Claudia, Kvasnicka Hans Michael, Varus Eva, Kleppe Stephanie, Beelen Dietrich Wilhelm, Schaefer Ullrich Wilhelm
Abstract excerpt
BACKGROUND: Although CD34 progenitors play a crucial role during bone marrow transplantation (BMT), there is only scant knowledge concerning their lineage-restricted mixed chimerism (MCh). METHODS: An immunohistochemical and fluorescence in situ hybridization study was performed on bone marrow biopsies derived from 11 patients with chronic myelogenous leukemia after sex-mismatched BMT to quantify the CD34 cell...
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