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A bacterial cell to cell signal in the lungs of cystic fibrosis patients

1 Sept 2002

Abstract excerpt

Pseudomonas aeruginosa is an opportunistic pathogen that is a major cause of mortality in cystic fibrosis (CF) patients. This bacterium has numerous genes controlled by cell to cell signaling, which occurs through a complex circuitry of interconnected regulatory systems. One of the signals is the Pseudomonas Quinolone Signal (PQS), which was identified as 2-heptyl-3-hydroxy-4-quinolone. This intercellular signal...

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Share to Bacterial biofilms and quorum sensing
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PMID: 12393198
DOI: 10.1111/j.1574-6968.2002.tb11367.x

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