Article
Pathogenesis and clinical management of hereditary non-polyposis colorectal cancer.
The British journal of surgery - 1 Nov 2002
Lawes D A, SenGupta S B, Boulos P B
Abstract excerpt
BACKGROUND: Hereditary non-polyposis colorectal cancer (HNPCC) is an inherited genetic condition associated with microsatellite instability; it accounts for around 5 per cent of all cases of colorectal cancer. This review examines recent data on management strategies for this condition. METHODS: A Medline-based literature search was performed using the keywords 'HNPCC' and 'microsatellite instability'. Additional...
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