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Article

Deficiency of antibacterial peptides in patients with morbus Kostmann: an observation study.

Lancet (London, England) - 12 Oct 2002

Pütsep Katrin, Carlsson Göran, Boman Hans G, Andersson Mats

Abstract excerpt

BACKGROUND: Antibacterial peptides, such as defensins and LL-37, are natural bactericidal components similar in potency to classic antibiotics. These peptides are produced at mucosal linings in the body and the skin, and by leucocytes such as neutrophils and natural killer cells. Patients with morbus Kostmann-a severe congenital neutropenia-are treated by recombinant granulocyte-colony stimulating factor, which...

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Source

Identifiers

PMID: 12387964
DOI: 10.1016/S0140-6736(02)11201-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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