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Article

Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities

16 Oct 2002

Abstract excerpt

Specific cytogenetic abnormalities predict prognosis in childhood acute myeloid leukemia (AML). However, it is unknown why they are predictive and whether this is related to drug resistance. We previously reported that Down syndrome (DS) AML was associated with favorable resistance profiles. Here, we successfully analyzed drug resistance and (cyto-) genetic abnormalities of 109 untreated childhood AML samples...

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PMID: 12384437
DOI: 10.1182/blood.v100.9.3352

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