Article
Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity.
Medicine - 1 Mar 2008
Bingham April, Mamyrova Gulnara, Rother Kristina I, Oral Elif, Cochran Elaine, Premkumar Ahalya, Kleiner David, James-Newton Laura, Targoff Ira N, Pandey Janardan P, Carrick Danielle Mercatante, Sebring Nancy, O'Hanlon Terrance P, Ruiz-Hidalgo Maria, Turner Maria, Gordon Leslie B, Laborda Jorge, Bauer Steven R, Blackshear Perry J, Imundo Lisa, Miller Frederick W, Rider Lisa G
Abstract excerpt
We describe the clinical features of 28 patients with juvenile dermatomyositis (JDM) and 1 patient with adult-onset dermatomyositis (DM), all of whom developed lipodystrophy (LD) that could be categorized into 1 of 3 phenotypes, generalized, partial, or focal, based on the pattern of fat loss distribution. LD onset was often delayed, beginning a median of 4.6 years after diagnosis of DM. Calcinosis, muscle...
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