Article
The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1.
Human molecular genetics - 15 Oct 2002
Akey Dayna T, Zhu Xuemei, Dyer Michael, Li Aimin, Sorensen Adam, Blackshaw Seth, Fukuda-Kamitani Taeko, Daiger Stephen P, Craft Cheryl M, Kamitani Tetsu, Sohocki Melanie M
Abstract excerpt
Mutations in the aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) gene have been found in patients with Leber congenital amaurosis (LCA), a severe, early-onset form of retinal degeneration. To determine the normal function of AIPL1 and to better understand how mutations in this gene cause disease, we performed a yeast two-hybrid screen to identify AIPL1-interacting proteins in the retina. One of the...
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