Article
Allelic imbalance and microsatellite instability in plasma DNA released from polyclonal pancreatic adenocarcinoma.
International journal of oncology - 1 Nov 2002
Moriyama H, Matsubara N, Kanbara T, Mori M, Matsuoka J, Yoshino T, Takakura N, Shimizu K, Takaka N
Abstract excerpt
Evidence of circulating soluble DNA in blood-stream of cancer patients has emerged. Because the plasma DNA is largely derived from cancer cells, genetic analysis of plasma DNA is important to understand the molecular events occurred in cancer patient. Seven microsatellite markers in the soluble plasma DNA from patients with pancreatic adenocarcinoma and other pancreato-biliary malignant tumors were examined for...
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