Article
The human L-threonine 3-dehydrogenase gene is an expressed pseudogene.
BMC genetics - 2 Oct 2002
Edgar Alasdair J
Abstract excerpt
BACKGROUND: L-threonine is an indispensable amino acid. One of the major L-threonine degradation pathways is the conversion of L-threonine via 2-amino-3-ketobutyrate to glycine. L-threonine dehydrogenase (EC 1.1.1.103) is the first enzyme in the pathway and catalyses the reaction: L-threonine + NAD+ = 2-amino-3-ketobutyrate + NADH. The murine and porcine L-threonine dehydrogenase genes (TDH) have been identified...
Topics
- Alcohol Oxidoreductases
- Amino Acid Sequence
- Base Sequence
- Cell Line
- Cells, Cultured
- Chromosome Mapping
- Codon, Terminator
- DNA Restriction Enzymes
- Genotype
- Humans
- Molecular Sequence Data
- Mutation
- Protein Structure, Secondary
- Pseudogenes
- RNA Splice Sites
- RNA, Messenger
- Sequence Alignment
- Sequence Analysis, DNA