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Article

Unusual phenotypic observations associated with a rare HbH disease genotype (- -Med/alphaTSaudialpha): implications for clinical management.

British journal of haematology - 1 Oct 2002

Traeger-Synodinos Joanne, Papassotiriou Ioannis, Karagiorga Markissia, Premetis Evangelos, Kanavakis Emmanuel, Stamoulakatou Alexandra

Abstract excerpt

A single patient with a rare Haemoglobin H (HbH) disease genotype (- -Med/alphaTSaudialpha) was observed to have exceptionally high levels of HbH (> 60%) and paradoxically high total haemoglobin levels. Studies of haematological parameters, blood biochemistry and oxygen transport properties revealed a severe functional anaemia, associated with marked erythropoietic stimulation and a markedly raised cardiac...

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Identifiers

PMID: 12358934
DOI: 10.1046/j.1365-2141.2002.03777.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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